Basically, what I'm asking is if any NPCs are marked 'essential', meaning they can't be killed whatsoever (and attacking them will simply incapacitate them for a short time whereupon they will get up and pretend nothing has happened).
Is it possible for me to kill everyone in Fallout 4? Or are there any NPCs that have been marked essential and thus impossible for me to kill?
72 Answers
No
If you attempt to kill some residents of Sanctuary, they will just fall to their knees and act disoriented. They will just get back up with their health fully regenerated after a minute or so.
3I killed everyone in Diamond City and they haven't respawned, only the kids are left.
However, killing everyone in the entire wasteland is a huge undertaking, which I've not accomplished.
1